7月12日美国西北大学Cheng Sun教授学术报告：High-throughput 3D Printing of Functional Biomedical Devices

报告题目：High-throughput 3D Printing of Functional Biomedical Devices
报告人：Prof. Cheng Sun
        Department of Mechanical Engineering,
        Northwestern University, USA
时间：2016年7月12日 (星期二)上午 10:00
地点：唐仲英楼 B501

附报告简介：

High-throughput 3D Printing of Functional Biomedical Devices

Cheng Sun
Department of Mechanical Engineering, Northwestern University, USA

Advancements in healthcare have opened up the promising opportunities for personalized medicine to improve patient outcomes while decreasing costs. However, widespread adoption remains a major challenge due to the additional time and expense required to individualize treatments to patient-specific conditions. Three-dimensional (3D) printing is an emerging technology with the potential to fabricate personalized biomedical devices at low cost with extremely short lead-time. Recent achievements in the field have utilized 3D printing to manufacture arterial stents, airway tubes, bones, and dental prosthetics with relative large dimensions. However, there remains a knowledge gap for the fabrication of biomedical device with fine feature size without compromising the fabrication speed. I will talk about a highly scalable 3D printing system - continuous liquid interface production microstereolithography (µCLIP) with sub-10 um fabrication precision.

I will present our recent development of fast 3D printing of completely customizable stents using the µCLIP process. Stents achieved a lateral resolution of 7.1 x 7.1 mm, with a curing thickness of 20 mm. A 20 mm length stent was printed in approximately 70 minutes and had adequate strength. The mechanical properties of 3D-printed stents with struts of 150 µm and walls thickness of 500 µm were comparable to those of a control bare metal nitinol stent. Furthermore, 3D-printed stents are customizable, could be compressed and self-expanded within a clinically relevant time frame upon deployment, and significantly improve the mechanical properties of a pig artery after deployment. Furthermore, I will discuss the method to fabricate a customized contact lens using 3D printed mold. The biocompatibility and optical performance of the lens has been further characterized experimentally using rat model.

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